-
Upregulation of long non‑coding RNA LINC00460 in EGFR‑mutant lung cancer indicates a poor prognosis in patients treated with osimertinib
- 著者
- Nakano, Yuta., Isobe, Kazutoshi., Yoshizawa, Takahiro., Urabe, Naohisa., Homma, Sakae., Kishi, Kazuma.
- 雑誌名
- Onco Lett
- DOI
- 10.3892/ol.2023.13966
- PMID
- 37559586
- Online published
- 2023 Jul 20
-
Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial
- 著者
- Mosele, Fernanda., Deluche, Elise., Lusque, Amelie., Le Bescond, Loïc., Filleron, Thomas., Pradat, Yoann., Ducoulombier, Agnes., Pistilli, Barbara., Bachelot, Thomas., Viret, Frederic., Levy, Christelle., Signolle, Nicolas., Alfaro, Alexia., T. N. Tran, Diep., Judith Garberis, Ingrid., Talbot, Hugues., Christodoulidis, Stergios., Vakalopoulou, Maria., Droin, Nathalie., Stourm, Aurelie., Kobayashi, Maki., Kakegawa, Tomoya., Lacroix, Ludovic., Saulnier, Patrick., Job, Bastien., Deloger, Marc., Jimenez, Marta., Mahier, Celine., Baris, Vianney., Laplante, Pierre., Kannouche, Patricia., Marty, Virginie., Lacroix-Triki, Magali., Diéras, Veronique., André, Fabrice.
- 雑誌名
- Nat Med
- 巻
- 29
- ページ
- 2110-2120
- 年
- 2023
- DOI
- 10.1038/s41591-023-02478-2
- PMID
- 37488289
- Online published
- 2023 Jul 24
-
Evaluation of control of additive concentration in gradient analysis of supercritical fluid chromatography-coupled to tandem mass spectrometry
- 著者
- Yamaguchi, Mayu., Tsuji, Makoto.
- 雑誌名
- J Chromatogr A
- DOI
- 10.1016/j.chroma.2023.464193
- PMID
- 37429077
- Online published
- 2023 Jul 02
-
N-Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors
- 著者
- Karanjule, Narayan., Hayashi, Noriyuki., Suzuki, Sayaka., Tsuda, Toshifumi., Tokumaru, Eri., Tanaka, Kyosuke., Kimoto, Hiroko., Domon, Yuki., Takahashi, Sakiko., Kubota, Kazufumi., Kitano, Yutaka., Yokoyama, Tomihisa., Koishi, Ryuta., Fujiwara, Chie., Inaba, Shinichi., Asano, Daigo., Sakakura, Tomoko., Takasuna, Kiyoshi., Shinozuka, Tsuyoshi.
- 雑誌名
- ACS Med Chem Lett
- DOI
- 10.1021/acsmedchemlett.3c00079
- PMID
- 37312847
- Online published
- 2023 Jun 08
-
Deep learning generates custom-made logistic regression models for explaining how breast cancer subtypes are classified
- 著者
- Shibahara, Takuma., Wada, Chisa., Yamashita, Yasuho., Fujita, Kazuhiro., Sato, Masamichi., Kuwata, Junichi., Okamoto, Atsushi., Ono, Yoshimasa.
- 雑誌名
- PLoS One
- DOI
- 10.1371/journal.pone.0286072
- PMID
- 37216350
- Online published
- 2023 May 22
-
Neuroprotection and axon regeneration by novel low-molecular-weight compounds through the modification of DOCK3 conformation
- 著者
- Namekata, Kazuhiko., Tsuji, Naoki., Guo, Xiaoli., Nishijima, Euido., Honda, Sari., Kitamura, Yuta., Yamasaki, Atsushi., Kishida, Masamichi., Takeyama, Jun., Ishikawa, Hirokazu., Shinozaki, Youichi., Kimura, Atsuko., Harada, Chikako., Harada, Takayuki.
- 雑誌名
- Cell Death Discov
- DOI
- 10.1038/s41420-023-01460-8
- PMID
- 37188749
- Online published
- 2023 May 15
-
Blood glucose trends in glycogen storage disease type Ia: A cross-sectional study
- 著者
- Fukuda,Tokiko., Ito, Tetsuya., Hamazaki, Takashi., Inui, Ayano., Ishige, Mika., Kagawa, Reiko., Sakai, Norio., Watanabe, Yoriko., Kobayashi, Hironori., Wasaki, Yosuke., Taura, Junki., Imamura, Yuki., Tsukiuda, Tsutomu., Nakamura, Kimitoshi.
- 雑誌名
- J Inherit Metab Dis
- DOI
- 10.1002/jimd.12610
- PMID
- 37114839
- Online published
- 2023 Apr 28
-
Suppression of TDP-43 aggregation by artificial peptide binder targeting to its low complexity domain
- 著者
- Kamagata, Kiyoto., Kanbayashi, Saori., Koda, Shuichi., Kadotani, Akito., Ubukata, Osamu., Tashima, Takumi.
- 雑誌名
- Biochem Biophys Res Commun
- DOI
- 10.1016/j.bbrc.2023.04.064
- PMID
- 37104882
- Online published
- 2023 Apr 20
-
Recognition mechanism of a novel gabapentinoid drug, mirogabalin, for recombinant human α2δ1, a voltage-gated calcium channel subunit
- 著者
- Kozai, Daisuke., Numoto, Nobutaka., Nishikawa, Kouki., Kamegawa, Akiko., Kawasaki, Shohei., Hiroaki, Yoko., Irie, Katsumasa., Oshima, Atsunori., Hanzawa, Hiroyuki., Shimada , Kousei., Kitano, Yutaka., Fujiyoshi, Yoshinori.
- 雑誌名
- J Mol Biol
- DOI
- 10.1016/j.jmb.2023.168049
- PMID
- 36933823
- Online published
- 2023 Mar 17
-
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1
- 著者
- Numata, Masashi., Haginoya, Noriyasu., Shiroishi, Machiko., Hirata, Tsuyoshi., Sato-Otsubo, Aiko., Yoshikawa, Kenji., Takata, Yoshimi., Nagase, Reina., Kashimoto, Yoshinori., Suzuki, Makoto., Schulte, Nina., Polier, Gernot., Kurimoto, Akiko., Tomoe, Yumiko., Toyota, Akiko., Yoneyama, Tomoko., Imai, Emi., Watanab, Kenji., Hamada, Tomoaki., Kanada, Ryutaro., Watanabe, Jun., Kagoshima, Yoshiko., Tokumaru, Eri., Murata, Kenji., Baba, Takayuki., Shinozaki, Taeko., Ohtsuka, Masami., Goto, Koichi., Karibe, Tsuyoshi., Deguchi, Takao., Gocho, Yoshihiro., Yoshida, Masanori., Tomizawa, Daisuke., Kato, Motohiro., Tsutsumi, Shinji., Kitagawa, Mayumi., Abe, Yuki.
- 雑誌名
- Cancer Cell Int
- DOI
- 10.1186/s12935-023-02877-y
- PMID
- 36841758
- Online published
- 2023 Feb 25
-
Changes in HER3 expression profiles between primary and recurrent gynecological cancers
- 著者
- Kojima,Yuki., Sudo, Kazuki., Yoshida, Hiroshi., Yazaki, Shu., Tokura, Momoko., Mizoguchi, Chiharu., Okuma S, Hitomi., Kita, Shosuke., Yamamoto, Kasumi., Nishikawa, Tadaaki., Noguchi, Emi., Shimoi, Tatsunori., Tanase, Yasuhito., Uno, Masaya., Ishikawa, Mitsuya., Kato, Tomoyasu., Koyama, Kumiko., Kobayashi, Maki., Kakegawa, Tomoya., Fujiwara, Yasuhiro., Yonemori, Kan.
- 雑誌名
- Cancer Cell Int
- DOI
- 10.1186/s12935-022-02844-z
- PMID
- 36737733
- Online published
- 2023 Feb 03
-
Selection of the methylotrophic yeast Ogataea minuta as a high-producing host for heterologous protein expression
- 著者
- Tsuda, Masashi., Nakatani, Yuki., Baba, Satoshi., Tanaka, Isshin., Ichikawa, Kimihisa., Nonaka, Koichi., Ito, Rie., Yoko-O, Takehiko., Chiba Yasunori.
- 雑誌名
- J Biosci Bioeng
- DOI
- 10.1016/j.jbiosc.2022.12.006
- PMID
- 36702678
- Online published
- 2023 Jan 24
-
Discovery of a novel ATP-competitive MEK inhibitor DS03090629 that overcomes resistance conferred by BRAF overexpression in BRAF-mutated melanoma
- 著者
- Takano, Kohei., Munehira, Yoichi., Hatanaka, Mana., Murakami, Ryo., Shibata, Yoshihiro., Shida, Takeshi., Takeuchi, Kosuke., Takechi, Sho., Tabata, Toshiki., Shimada, Takashi., Kishikawa, Shuhei., Matsui, Yumi., Ubukata, Osamu., Seki, Takahiko., Kaneta, Yasuyuki.
- 雑誌名
- Mol Cancer Ther
- DOI
- 10.1158/1535-7163.MCT-22-0306
- PMID
- 36622773
- Online published
- 2023 Jan 09
-
Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor
- 著者
- Kanada, Ryutaro., Kagoshima, Yoshiko., Suzuki, Takashi., Nakamura, Akifumi., Funami, Hideaki., Watanabe, Jun., Asano, Masayoshi., Takahashi, Mizuki., Ubukata, Osamu., Suzuki, Kanae., Aikawa, Tomoya., Sato, Kazumi., Goto, Megumi., Setsu, Genzui., Ito, Kentaro., Kihara, Kawori., Kuroha, Mutsumi., Kohno, Takashi., Ogiwara, Hideaki., Isoyama, Takeshi., Tominaga, Yuichi., Higuchi, Saito., Naito, Hiroyuki.
- 雑誌名
- J Med Chem
- DOI
- 10.1021/acs.jmedchem.2c01641
- PMID
- 36572866
- Online published
- 2022 Dec 26
-
Inhibition of Liquid–Liquid Phase Separation for Breaking the Solubility Barrier of Amorphous Solid Dispersions to Improve Oral Absorption of Naftopidil
- 著者
- Fukiage, Masafumi., Suzuki, Kyosuke., Matsuda, Maki., Nishida, Yohei., Oikawa, Michinori., Fujita, Takuya., Kawakami, Kohsaku.
- 雑誌名
- Pharmaceutics
- DOI
- 10.3390/pharmaceutics14122664
- PMID
- 36559158
- Online published
- 2022 Nov 30
-
Practical Synthetic Method of Ogipeptin Derivatives
- 著者
- Takiguchi, Shingo., Nishi, Takahide.
- 雑誌名
- Synlett
- DOI
- 10.1055/a-1981-4379
- PMID
- Online published
- 2022 Nov 17
-
Inflammation of the cardiac coronary artery in ICR mice
- 著者
- Yasuno,Kyohei., Imaoka, Masako., Ohsawa, Tetsuya., Okado, Keiko., Kai, Kiyonori., Tsuchiya, Yoshimi.
- 雑誌名
- J Toxicol Pathol
- DOI
- 10.1293/tox.2022-0022
- PMID
- 36406175
- Online published
- 2022 Jun 11
-
Identification and characterization of lysophosphatidylcholine 14:0 as a biomarker for drug-induced lung disease
- 著者
- Saito, Kosuke., Gemma, Akihiko., Tatsumi, Koichiro., Hattori, Noboru., Ushiki, Atsuhito., Tsushima, Kenji., Saito, Yoshinobu., Abe, Mitsuhiro., Horimasu, Yasushi., Kashiwada, Takeru., Mori, Kazuhiko., Sato, Motonobu., Nishiya, Takayoshi., Takamatsu, Kazuhiko., Sun, Yuchen., Arakawa, Noriaki., Izumi, Takashi., Ohno, Yasuo., Saito, Yoshiro., Hanaoka, Masayuki.
- 雑誌名
- Sci Rep
- DOI
- 10.1038/s41598-022-24406-z
- PMID
- 36396675
- Online published
- 2022 Nov 17
-
Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals
- 著者
- Fukuchi, Keisuke., Nanai, Kayoko., Yuita, Hiroshi., Maru, Chikako., Tsukada, Jun., Ishigami, Masato., Nagai, Yoko., Nakano, Yoko., Yoshimura, Chigusa., Yoneda, Kozo., Amano, Masato., Nakamura, Kensuke., Oda, Yoko., Nishigohri, Haruyuki., Yamamoto, Shoji., Ohnishi-Totoki, Yusuke., Inaki, Koichiro., Komori, Hironobu., Nakano, Rika., Kanari, Yoshiyuki., Nishida, Atsuko., Matsui, Yumi., Funo, Satoko., Takahashi, Sayako., Ohtsuka, Toshiaki., Agatsuma, Toshinori.
- 雑誌名
- J Oncol
- 巻
- 2022
- ページ
- 3552793
- 年
- 2022
- DOI
- 10.1155/2022/3552793
- PMID
- 36385956
- Online published
- 2022 Nov 04
-
Spatial and Quantitative Analysis of Tumor-Associated Macrophages: Intratumoral CD163-/PD-L1+ TAMs as a Marker of Favorable Clinical Outcomes in Triple-Negative Breast Cancer
- 著者
- Shinohara, Hajime., Kobayashi, Maki., Hayashi, Kumiko., Nogawa, Daichi., Asakawa, Ayaka., Ohata, Yae., Kubota, Kazuishi., Takahashi, Hisashi., Yamada, Miyuki., Tokunaga, Masanori., Kinugasa, Yusuke., Oda, Goshi., Nakagawa, Tsuyoshi., Onishi, Iichiroh., Kinowaki, Yuko., Kurata, Morito., Ohashi, Kenichi., Kitagawa, Masanobu., Yamamoto, Kouhei.
- 雑誌名
- Int J Mol Sci
- DOI
- 10.3390/ijms232113235
- PMID
- 36362023
- Online published
- 2022 Oct 31
-
The Novel Gabapentinoid Mirogabalin Prevents Upregulation of α2δ-1 Subunit of Voltage-Gated Calcium Channels in Spinal Dorsal Horn in a Rat Model of Spinal Nerve Ligation
- 著者
- Domon,Yuki., Kobayashi, Naoko., Kubota, Kazufumi., Kitano, Yutaka., Ueki, Hideaki., Shimojo, Yumiko., Ishikawa, Kayoko., Ofune, Yuka.
- 雑誌名
- Drug Res (Stuttg)
- DOI
- 10.1055/a-1941-8907
- PMID
- 36216339
- Online published
- 2022 Oct 10
-
Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage
- 著者
- Arakawa,Noriaki., Ushiki, Atsuhito., Abe, Mitsuhiro., Matsuyama, Shinichiro., Saito, Yoshinobu., Kashiwada, Takeru., Horimasu, Yasushi., Gemma, Akihiko., Tatsumi, Koichiro., Hattori, Noboru., Tsushima, Kenji., Miyashita, Keiko., Saito, Kosuke., Nakamura, Ryosuke., Toyoda, Takeshi., Ogawa, Kumiko., Sato, Motonobu., Takamatsu, Kazuhiko., Mori, Kazuhiko., Nishiya, Takayoshi., Izumi, Takashi., Ohno, Yasuo., Saito, Yoshiro., Hanaoka, Masayuki.
- 雑誌名
- Nat Commun
- DOI
- 10.1038/s41467-022-33160-9
- PMID
- 36195613
- Online published
- 2022 Oct 04
-
Effect of Trastuzumab Deruxtecan on QT/QTc Interval and Pharmacokinetics in HER2-Positive or HER2-Low Metastatic/Unresectable Breast Cance
- 著者
- Shimomura, Akihiko., Takano, Toshimi., Takahashi, Shunji., Sagara, Yasuaki., Watanabe, Junichiro., Tokunaga, Eriko., Shinkai, Tetsu., Kamio, Takahiro., Kikumori, Kunika., Kamiyama, Emi., Fujisaki, Yoshihiko., Saotome, Dan., Yamashita, Toshinari.
- 雑誌名
- Clin Pharmacol Ther
- DOI
- 10.1002/cpt.2757
- PMID
- 36164935
- Online published
- 2022 Sep 27
-
Quantitative high-throughput analysis of tumor infiltrating lymphocytes in breast cancer
- 著者
- Hayashi, Kumiko., Nogawa, Daichi., Kobayashi, Maki., Asakawa, Ayaka., Ohata, Yae., Kitagawa, Shota., Kubota, Kazuishi., Takahashi, Hisashi., Yamada, Miyuki., Oda, Goshi., Nakagawa, Tsuyoshi., Uetake, Hiroyuki., Onishi, Iichiroh., Kinowaki, Yuko., Kurata, Morito., Kitagawa, Masanobu., Yamamoto, Kouhei.
- 雑誌名
- Front Oncol
- DOI
- 10.3389/fonc.2022.901591
- PMID
- 36132149
- Online published
- 2022 Sep 05
-
Pan-cancer gene expression analysis of tissue microarray using EdgeSeq oncology biomarker panel and a cross-comparison with HER2 and HER3 immunohistochemical analysis
- 著者
- Inaki,Koichiro., Shibutani, Tomoko., Maeda, Naoyuki., Eppenberger-Castori, Serenella., Nicolet, Stefan., Kaneda, Yuki., Koyama, Kumiko., Qiu, Yang., Wakita, Kenichi., Murakami, Masato.
- 雑誌名
- PLoS One
- DOI
- 10.1371/journal.pone.0274140
- PMID
- 36137139
- Online published
- 2022 Sep 22
-
Potent and selective PTDSS1 inhibitors induce collateral lethality in cancers with PTDSS2 deletion
- 著者
- Yoshihama,Yohei., Namiki, Hidenori., Kato, Taiga., Shimazaki, Naomi., Takaishi, Sachiko., Kadoshima-Yamaoka, Kumiko., Yukinaga, Hideo., Maeda, Naoyuki., Shibutani, Tomoko., Fujimoto, Kazunori., Hirasawa, Makoto., Goto, Hiroki., Wada, Naoya., Tsutsumi, Shinji., Hirota, Yasuhide., Ishikawa, Tomoki., Yamamoto, Shoji.
- 雑誌名
- Cancer Res
- 巻
- 82
- ページ
- 4031-4043
- 年
- 2022
- DOI
- 10.1158/0008-5472.CAN-22-1006
- PMID
- 36054550
- Online published
- 2022 Sep 02
-
Identification and characterization of a novel thermo-stable endo-β-N-acetylglucosaminidase from Rhizomucorpusillus
- 著者
- Nishizawa, Hanako., Iwamoto, Mitsuhiro., Ono, Yasunori.
- 雑誌名
- J Biosci Bioeng
- DOI
- 10.1016/j.jbiosc.2022.06.013
- PMID
- 35961816
- Online published
- 2022 Aug 10
-
Novel protein kinase cAMP-Activated Catalytic Subunit Alpha (PRKACA) inhibitor shows anti-tumor activity in a fibrolamellar hepatocellular carcinoma model
- 著者
- Toyota, Akiko., Goto, Megumi., Miyamoto, Masaya., Nagashima, Yoko., Iwasaki, Shiho., Komatsu, Takahiro., Momose, Takayuki., Yoshida, Keisuke., Tsukada, Tomoharu., Matsufuji, Tetsuyoshi., Ohno, Ami., Suzuki, Makoto., Ubukata, Osamu., Kaneta, Yasuyuki.
- 雑誌名
- Biochem Biophys Res Commun
- DOI
- 10.1016/j.bbrc.2022.07.008
- PMID
- 35839742
- Online published
- 2022 Jul 07
-
Impact of the Clinical Trials Act 2018 on clinical trial activity in Japan from 2018 to 2020: a retrospective database study using new and conventional Japanese registries
- 著者
- Taruno, Hiroyuki., Oba, Mari S., Takizawa, Osamu., Kikuchi, Kayoko., Matsui, Kazuaki., Shikano, Mayumi.
- 雑誌名
- BMJ Open
- DOI
- 10.1136/bmjopen-2021-059092
- PMID
- 35851007
- Online published
- 2022 Jul 18
-
Total Synthesis and Structural Elucidation of Ogipeptins
- 著者
- Takiguchi, Shingo., Hirota-Takahata,Yuki., Nishi, Takahide.
- 雑誌名
- Org Lett
- 巻
- 24
- ページ
- 4935-4938
- 年
- 2022
- DOI
- 10.1021/acs.orglett.2c01863
- PMID
- 35796660
- Online published
- 2022 Jul 07
-
Systematic Exploration of Passive Permeability in Tetrapeptides with Hydrogen–Bond Accepting Amino Acid Side Chains
- 著者
- Shimizu, Hiroki., Renslo, Adam.
- 雑誌名
- ChemMedChem
- 巻
- 17
- ページ
- e202200204
- 年
- 2022
- DOI
- 10.1002/cmdc.202200204
- PMID
- 35696654
- Online published
- 2022 Jun 13
-
Microarray-based gene expression analysis combined with laser capture microdissection is beneficial in investigating the modes of action of ocular toxicity
- 著者
- Shirai, Makoto., Niino, Noriyo., Mori, Kazuhiko., Kai, Kiyonori.
- 雑誌名
- J Toxicol Pathol
- DOI
- 10.1293/tox.2021-0064
- PMID
- 35516843
- Online published
- 2021 Dec 18
-
Patritumab deruxtecan (HER3-DXd), a novel HER3 directed antibody drug conjugate, exhibits in vitro activity against breast cancer cells expressing HER3 mutations with and without HER2 overexpression
- 著者
- Koyama ,Kumiko., Ishikawa, Hirokazu., Abe, Manabu., Shiose, Yoshinobu., Ueno, Suguru., Qiu, Yang., Nakamaru, Kenji., Murakami, Masato.
- 雑誌名
- PLoS One.
- DOI
- 10.1371/journal.pone.0267027
- PMID
- 35503762
- Online published
- 2022 May 03
-
Determination of key residues in MRGPRX2 to enhance pseudo-allergic reactions induced by fluoroquinolones
- 著者
- Hamamura-Yasuno, Eri., Matsushita, Junya., Sato, Seiji., Shimada, Takashi., Tsuchiya, Yoshimi., Fujimoto, Kazunori., Mori, Kazuhiko.
- 雑誌名
- Sci Rep.
- DOI
- 10.1038/s41598-022-10549-6.
- PMID
- 35459883
- Online published
- 2022 Apr 22
-
Application of the advanced Marfey’s method for the determination of the absolute configuration of ogipeptins
- 著者
- Takiguchi, Shingo., Hirota-Takahata, Yuki., Nishi, Takahide.
- 雑誌名
- Tetrahedron Letters
- DOI
- 10.1016/j.tetlet.2022.153760
- PMID
- Online published
- 2022 Mar 30
-
Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring
- 著者
- Kanada, Ryutaro., Kagoshima, Yoshiko., Asano, Masayoshi., Suzuki, Takashi., Murata, Takeshi., Haruta, Makoto., Takahashi, Mizuki., Ubukata, Osamu., Hashimoto, Kazuyuki., Obata, Kenichi., Kihara, Kawori., Kuroha, Mutsumi., Banjo, Toshihiro., Togashi, Noriko., Sato, Kazumi., Yamamoto, Yuka., Suzuki, Kanae., Isoyama, Takeshi., Tominaga, Yuichi., Higuchi, Saito., Naito, Hiroyuki.
- 雑誌名
- Bioorg Med Chem Lett
- DOI
- 10.1016/j.bmcl.2022.128726
- PMID
- 3541341
- Online published
- 2022 Apr 09
-
CYP2C8-Mediated Formation of a Human Disproportionate Metabolite of the Selective Na V 1.7 Inhibitor DS-1971a, a Mixed Cytochrome P450 and Aldehyde Oxidase Substrate
- 著者
- Asano, Daigo., Hamaue, Syoya., Zahir, Hamim., Shiozawa, Hideyuki ., Nishiya, Yumi., Kimura, Takako., Kazui, Miho., Yamamura, Naotoshi., Ikeguchi, Marie., Shibayama, Takahiro., Inoue, Shin-Ichi., Shinozuka, Tsuyoshi., Watanabe, Toshiyuki., Yahara, Chizuko., Watanabe, Nobuaki., Yoshinari, Kouichi.
- 雑誌名
- Drug Metab Dispos
- DOI
- 10.1124/dmd.121.000665
- PMID
- 34930785
- Online published
- 2021 Dec 20
-
DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-based Antibody-Drug Conjugate Targeting B7-H3 Exerts Potent Antitumor Activities in Preclinical Models
- 著者
- Yamato,Michiko., Hasegawa, Jun., Maejima, Takanori., Hattori, Chiharu., Kumagai, Kazuyoshi., Watanabe, Akiko., Nishiya, Yumi., Shibutani, Tomoko., Aida, Tetsuo., Hayakawa, Ichiro., Nakada, Takashi., Abe, Yuki., Agatsuma, Toshinori.
- 雑誌名
- Mol Cancer Ther
- DOI
- 10.1158/1535-7163.MCT-21-0554
- PMID
- 35149548
- Online published
- 2022 Feb 11
-
A gut-derived metabolite alters brain activity and anxiety behaviour in mice
- 著者
- Needham, Brittany D., Funabashi, Masanori., Adame, Mark D., Wang, Zhuo., Boktor, Joseph C., Haney, Jillian., Wu, Wei-Li., Rabut, Claire., Ladinsky, Mark S., Hwang, Son-Jong., Guo, Yumei., Zhu, Qiyun., Griffiths, Jessica A., Knight , Rob., Bjorkman, Pamela J., Shapiro, Mikhail G., Geschwind, Daniel H., Holschneider, Daniel P., Fischbach, Michael A., Mazmanian, Sarkis K.
- 雑誌名
- Nature
- DOI
- 10.1038/s41586-022-04396-8
- PMID
- 35165440
- Online published
- 2022 Feb 14
-
HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non-Small Cell Lung Cancer
- 著者
- Yonesaka, Kimio., Tanizaki, Junko., Maenishi, Osamu., Haratani, Koji., Kawakami, Hisato., Tanaka, Kaoru., Hayashi, Hidetoshi., Sakai, Kazuko., Chiba, Yasutaka., Tsuya, Asuka., Goto, Hiroki., Otsuka, Eri., Okida, Hiroaki., Kobayashi, Maki., Yoshimoto, Ryoto., Funabashi, Masanori., Hashimoto, Yuuri., Hirotani, Kenji., Kagari, Takashi., Nishio, Kazuto., Nakagawa, Kazuhiko.
- 雑誌名
- Clin Cancer Res .
- DOI
- 10.1158/1078-0432.CCR-21-3359
- PMID
- 34921025
- Online published
- 2021 Dec 17
-
Analysis of fluoroquinolone-resistance using MIC determination and homology modelling of ParC of contemporary Mycoplasma genitalium strains
- 著者
- Hamasuna, Ryoichi., Hanzawa, Hiroyuki., Moritomo, Ayako., Matsumoto, Masahiro., Aono, Hisami., Tomisaki, Ikko., Akasaka, Takaaki., Fujimoto, Naohiro., SkovJensen, Jørgen.
- 雑誌名
- J Infect Chemother
- DOI
- 10.1016/j.jiac.2021.11.011
- PMID
- 34836778
- Online published
- 2021 Nov 24
-
Highly sensitive in vitro cytokine release assay incorporating high-density preculture
- 著者
- Ito, Shiho., Miwa, Kyoko., Hattori, Chiharu., Aida, Tetsuo., Tsuchiya, Yoshimi., Mori, Kazuhiko.
- 雑誌名
- J Immunotoxicol
- DOI
- 10.1080/1547691X.2021.1984617
- PMID
- 34644231
- Online published
- 2021 Oct 13
-
Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells
- 著者
- Okajima, Daisuke.,Yasuda, Satoru., Maejima, Takanori., Karibe, Tsuyoshi., Sakurai, Ken., Aida, Tetsuo., Toki, Tadashi., Yamaguchi, Junko., Kitamura, Michiko., Kamei, Reiko., Fujitani, Tomomichi., Honda, Tomoyo., Shibutani, Tomoko., Muramatsu, Sumie., Nakada, Takashi., Goto, Riki., Takahashi, Shu., Yamaguchi, Miki., Hamada, Hirofumi., Noguchi, Yutaka., Murakami, Masato., Abe, Yuki., Agatsuma, Toshinori.
- 雑誌名
- Mol Cancer Ther
- 巻
- 20
- ページ
- 2329-2340
- 年
- 2021
- DOI
- 10.1158/1535-7163.MCT-21-0206
- PMID
- 34413126
- Online published
- 2021 Aug 19
-
Expanded precision medicine capabilities for strengthening oncology drug development at Daiichi Sankyo
- 著者
- Murakami, Masato., Tokui, Taro., Nakamaru, Kenji., Cogswell, John., Ford, Shirin Khambata., Gallant, Gilles.
- 雑誌名
- Journal of Precision Medicine
- DOI
- https://www.thejournalofprecisionmedicine.com/wp-content/uploads/expanded-precision.pdf
- PMID
- Online published
-
4-Pyridone-3-carboxylic acid as a benzoic acid bioisostere: Design, synthesis, and evaluation of EP300/CBP histone acetyltransferase inhibitors
- 著者
- Kanada, Ryutaro., Suzuki, Takashi., Murata, Takeshi., Miyazaki, Masaki., Shimada, Takashi., Kuroha, Mutsumi., Minami, Megumi., Higuchi, Saito., Tominaga, Yuichi., Naito, Hiroyuki.
- 雑誌名
- Bioorg Med Chem Lett
- DOI
- 10.1016/j.bmcl.2021.128358
- PMID
- 34534674
- Online published
- 2021 Sep 14
-
New biphasic system in side-by-side chambers for testing drug dissolution and permeation in vitro (BiDP system)
- 著者
- Masada,Takato., Takagi, Toshihide., Minami, Keiko., Kataoka, Makoto., Takeyama, Shoko., Fujii, Yoshimine., Takahashi, Masayuki., Yamashita, Shinji.
- 雑誌名
- Journal of Drug Delivery Science and Technology
- DOI
- 10.1016/j.jddst.2021.102747
- PMID
- Online published
- 2021 Jul 24
-
Reforms of regulatory pathways for approval of new antineoplastic drugs in Japan from 2004 to 2019 and accompanying changes in pivotal clinical trial designs
- 著者
- Hirai, Takehiro., Suzuki, Asuka., Yamori, Takao., Matsuura, Masaaki.
- 雑誌名
- Invest New Drugs
- DOI
- 10.1007/s10637-021-01165-8
- PMID
- 34417913
- Online published
- 2021 Aug 21
-
A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
- 著者
- Furuzono, Shinji., Kubota,Tetsuya., Taura, Junki., Konishi, Masahiro.,
Naito, Asuka., Tsutsui, Masato., Karasawa, Hiroshi., Kubota, Naoto., Kadowaki, Takashi.
- 雑誌名
- Commun Biol
- DOI
- 10.1038/s42003-021-02491-6
- PMID
- 34417555
- Online published
- 2021 Aug 20
-
Novel anti-GARP antibody DS-1055a augments anti-tumor immunity by depleting highly suppressive GARP+ regulatory T cells
- 著者
- Satoh, Kazuki., Kobayashi, Yoichi., Fujimaki, Kaori., Hayashi, Shinko., Ishida, Saori., Sugiyama, Daisuke., Sato, Takahiko., Lim, Kyungtaek., Miyamoto, Megumi., Kozuma, Shiho., Kadokura, Michinori., Wakita, Kenichi., Hata, Masato., Hirahara, Kazuki., Amano, Masato., Watanabe, Ichiro., Okamoto, Atsushi., Tuettenberg, Andrea., Jonuleit, Helmut., Tanemura, Atsushi., Maruyama, Shoichi., Agatsuma, Toshinori., Wada, Teiji., Nishikawa, Hiroyoshi.
- 雑誌名
- Int Immunol
- DOI
- 10.1093/intimm/dxab027
- PMID
- 34235533
- Online published
- 2021 Jun 03
-
Corrigendum to “Syntheses and antimicrobial activities of ogipeptin derivatives” [Bioorg. Med. Chem. Lett. 42 (2021) 128093]
- 著者
- Takiguchi, Shingo., Homma, Hidehito., Fujisawa, Tetsunori., Hirota-Takahata, Yuki., Ono, Yasunori., Kizuka, Masaaki., Ishii, Yuki., Yoshimura, Satomichi., Nishi, Takahide.
- 雑誌名
- Bioorg Med Chem Lett
- DOI
- 10.1016/j.bmcl.2021.128228
- PMID
- 34192636
- Online published
- 2021 Jun 27
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