主な投稿論文

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Achievements主な投稿論文

  • Design, synthesis, and pharmacological evaluation of a novel series of hormone sensitive lipase inhibitor
    著者
    Ogiyama, Tomoko., Yamaguchi, Mitsuhiro., Kurikawa, Nobuya., Honzumi, Shoko., Terayama, Koji., Nagaoka, Nobumi., Yamamoto, Yuka., Kimura, Takako., Sugiyama, Daisuke., Inoue, Shin-Ichi.
    雑誌名
    Bioorganic & medicinal chemistry
    25
    ページ
    4817-4828
    2017
    DOI
    10.1016/j.bmc.2017.07.028
    PMID
    28756012
    Online published
    2017 Jul 17
  • Pathological and gene expression analysis of a polygenic diabetes model, NONcNZO10/LtJ mice
    著者
    Hirata, Tsuyoshi., Yoshitomi, Tomomi., Inoue, Minoru., Iigo, Yutaka., Matsumoto, Koji., Kubota, Kazuishi., Shinagawa, Akira.
    雑誌名
    Gene
    629
    ページ
    52-58
    2017
    DOI
    10.1016/j.gene.2017.07.075
    PMID
    28760554
    Online published
    2017 Jul 29
  • Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor
    著者
    Honma, Daisuke., Kanno, Osamu., Watanabe, Jun., Kinoshita, Junzo., Hirasawa, Makoto., Nosaka, Emi., Shiroishi, Machiko., Takizawa, Takeshi., Yasumatsu, Isao., Horiuchi, Takao., Nakao, Akira., Suzuki, Keisuke., Yamasaki, Tomonori., Nakajima, Katsuyoshi., Hayakawa, Miho., Yamazaki, Takanori., Yadav, Ajay Singh., Adachi, Nobuaki.
    雑誌名
    Cancer science
    108
    ページ
    2069-2078
    2017
    DOI
    10.1111/cas.13326
    PMID
    28741798
    Online published
    2017 Aug 08
  • Dystrophin Dp116: A yet to Be Investigated Product of the Duchenne Muscular Dystrophy Gene
    著者
    Matsuo, Masafumi., Awano, Hiroyuki., Matsumoto, Masaaki., Nagai, Masashi., Kawaguchi, Tatsuya., Zhang, Zhujun., Nishio, Hisahide.
    雑誌名
    Genes
    8
    ページ
    251
    2017
    DOI
    10.3390/genes8100251
    PMID
    Online published
    2017 Oct 02
  • F-36316 A and B, novel vasoactive compounds, isolated from Incrucipulum sp. SANK 10414
    著者
    Hirota-Takahata, Yuki., Ishimoto, Yoko., Kurosawa, Emi., Iwadate, Yuko., Onozawa, Yoshiko., Tanaka, Isshin., Tanaka, Masahiro., Kobayashi, Hideki.
    雑誌名
    The Journal of antibiotics
    70
    ページ
    981-986
    2017
    DOI
    10.1038/ja.2017.84
    PMID
    28792011
    Online published
    2017 Aug 09
  • TLR7 mediated viral recognition results in focal type i interferon secretion by dendritic cells
    著者
    Saitoh, Shin Ichiroh., Abe, Fumiko., Kanno, Atsuo., Tanimura, Natsuko., Mori Saitoh, Yoshiko., Fukui, Ryutaro., Shibata, Takuma., Sato, Katsuaki., Ichinohe, Takeshi., Hayashi, Mayumi., Kubota, Kazuishi., Kozuka-Hata, Hiroko., Oyama, Masaaki., Kikko, Yorifumi., Katada, Toshiaki., Kontani, Kenji., Miyake, Kensuke.
    雑誌名
    Nature Communications
    8
    ページ
    1592
    2017
    DOI
    10.1038/s41467-017-01687-x
    PMID
    Online published
    2017 Nov 17
  • Memantine inhibits β-amyloid aggregation and disassembles preformed β-amyloid aggregates
    著者
    Takahashi-Ito, Kaori., Makino, Mitsuhiro., Okado, Keiko., Tomita, Taisuke.
    雑誌名
    Biochemical and Biophysical Research Communications
    493
    ページ
    158-163
    2017
    DOI
    10.1016/j.bbrc.2017.09.058
    PMID
    Online published
    2017 Sep 14
  • Difference in mechanism-based inhibition of cytochrome P450 3A4 and 3A5 by a series of fluoroquinolone antibacterial agents
    著者
    Watanabe, Akiko., Takakusa, Hideo., Kimura, Takako., Inoue, Shin Ichi., Kusuhara, Hiroyuki., Ando, Osamu.
    雑誌名
    Drug Metabolism and Disposition
    45
    ページ
    336-341
    2017
    DOI
    10.1124/dmd.116.073783
    PMID
    Online published
    2016 Dec 14
  • Memantine reduces the production of amyloid-β peptides through modulation of amyloid precursor protein trafficking
    著者
    Ito, Kaori., Tatebe, Takuya., Suzuki, Kunimichi., Hirayama, Takashi., Hayakawa, Maki., Kubo, Hideo., Tomita, Taisuke., Makino, Mitsuhiro.
    雑誌名
    European Journal of Pharmacology
    798
    ページ
    16-25
    2017
    DOI
    10.1016/j.ejphar.2017.02.001
    PMID
    Online published
    2017 Feb 04
  • Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells
    著者
    Tachida, Yuki., Izumi, Nanae., Sakurai, Toyo., Kobayashi, Hideki.
    雑誌名
    Biology open
    6
    ページ
    370-380
    2017
    DOI
    10.1242/bio.020503
    PMID
    28298363
    Online published
    2017 Mar 15
  • Discovery and pharmacological effects of a novel GPR142 antagonist
    著者
    Murakoshi, Michiko., Kuwabara, Harumi., Nagasaki, Miyuki., Xiong, Yu Mei., Reagan, Jeff D.., Maeda, Hiroaki., Nara, Futoshi.
    雑誌名
    Journal of Receptors and Signal Transduction
    37
    ページ
    290-296
    2017
    DOI
    10.1080/10799893.2016.1247861
    PMID
    Online published
    2016 Nov 03
  • DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter
    著者
    Kon, Naohiro., Murakoshi, Michiko., Isobe, Aya., Kagechika, Katsuji., Miyoshi, Naoki., Nagayama, Takahiro.
    雑誌名
    Cell death discovery
    3
    ページ
    17045
    2017
    DOI
    10.1038/cddiscovery.2017.45
    PMID
    28725491
    Online published
    2017 Jul 17
  • Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
    著者
    Matsui, Yumi., Yasumatsu, Isao., Asahi, Takashi., Kitamura, Takahiro., Kanai, Kazuo., Ubukata, Osamu., Hayasaka, Hitoshi., Takaishi, Sachiko., Hanzawa, Hiroyuki., Katakura, Shinichi.
    雑誌名
    Bioorganic & medicinal chemistry
    25
    ページ
    3540-3546
    2017
    DOI
    10.1016/j.bmc.2017.05.004
    PMID
    28511909
    Online published
    2017 May 05
  • Ogipeptins, novel inhibitors of LPS: physicochemical properties and structural elucidation
    著者
    Hirota-Takahata, Yuki., Kozuma, Shiho., Kuraya, Nahoki., Fukuda, Daisuke., Nakajima, Mutsuo., Takatsu, Toshio., Ando, Osamu.
    雑誌名
    The Journal of antibiotics
    70
    ページ
    84-89
    2017
    DOI
    10.1038/ja.2016.61
    PMID
    27328866
    Online published
    2016 Jun 22
  • Quantitative Structure-activity Relationship (QSAR) Models for Docking Score Correction
    著者
    Fukunishi, Yoshifumi., Yamasaki, Satoshi., Yasumatsu, Isao., Takeuchi, Koh., Kurosawa, Takashi., Nakamura, Haruki.
    雑誌名
    Molecular Informatics
    36
    ページ
    1600013
    2017
    DOI
    10.1002/minf.201600013
    PMID
    Online published
    2016 Apr 29
  • Identification and biological activity of ogipeptins, novel LPS inhibitors produced by marine bacterium
    著者
    Kozuma, Shiho., Hirota-Takahata, Yuki., Fukuda, Daisuke., Kuraya, Nahoki., Nakajima, Mutsuo., Ando, Osamu.
    雑誌名
    The Journal of antibiotics
    70
    ページ
    79-83
    2017
    DOI
    10.1038/ja.2016.81
    PMID
    27381520
    Online published
    2016 Jul 06
  • Vestaines, novel vasoactive compounds, isolated from Streptomyces sp. SANK 63697
    著者
    Hirota-Takahata, Yuki., Kurosawa, Emi., Ishimoto, Yoko., Iwadate, Yuko., Kizuka, Masaaki., Chiba, Jun., Hasegawa, Toru., Tanaka, Masahiro., Kobayashi, Hideki.
    雑誌名
    Journal of Antibiotics
    70
    ページ
    179-186
    2017
    DOI
    10.1038/ja.2016.98
    PMID
    Online published
    2016 Aug 17