Daiichi Sankyo RD Novare, a technology-led company
that is the driving force behind new drug discoveries.
As a new challenge, the Clinical Research Laboratory
has committed to accelerating oncology research and development.
The ardent desire of all Daiichi Sankyo RD Novare employees
is to make as many patients smile as we can with our technologies.
Our objective is to create drugs that are really effective
for each and every patient.
To do so, we initiated a challenge to transform the drug discovery process.
The application of knowledge and technologies developed in nonclinical research to the analysis of clinical specimens will lead to an accurate understanding of the mechanisms of disease occurring in humans and lead to the discovery of new drugs.
In the future, we aim to become a leading player in the drug discovery ecosystem by analyzing cancer clinical samples in collaboration with multiple clinical institutions.
The laboratory went into full operation in April 2019.
We introduced state-of-the-art technologies and equipment, and ensured
the reliability of data and information through the organizational operation
of GCP compliance.
The main axis of the lab is genomics.
Multilayered and precise analysis is being achieved by conducting research in conjunction with informatics, molecular pathology, and genomics.
In addition, we are focusing on the construction of sophisticated IT systems that ensure security and the establishment of a system for quality assurance.
We believe it is possible to ensure the reliability of laboratories by properly processing the complex and vast amounts of human genome information and by handling it safely in accordance with the Personal Information Protection Law.
Analyze what is happening at the lesion site
Molecular Pathology Group
In molecular pathology, we perform highly precise clinical research
by correctly handling clinical specimens and identifying lesions
based on histopathological knowledge.
By visualizing the changes in expression and by localizing target molecules, we analyze what happens at the lesion site.
Analyze gene expression and genetic mutations
in collaboration with molecular pathology
Genetic analysis involves analyzing gene expression and mutations
in conjunction with molecular pathology.
For example, we improve our understanding of the effects and side effects of drugs by analyzing cancer tissues and the microenvironment surrounding the cancer tissues, and by performing correlative analyses between histopathology and gene expression.
Genomic analysis of clinical samples is also
the ultimate analysis of personal information.
Therefore, we have constructed a rigorous and robust system to accurately track samples and manage data.
Understand diseases mechanism and
generate hypotheses by genomic analysis
On the basis of this robust and secure analysis environment,
we are working to understand diseases at the genome
and even the epigenome level by using a variety of
genomics analysis techniques and
sophisticated informatics techniques
with appropriate processing of specimens.